Scientific American   Last month, an op–ed in The New York Times argued
 that high-protein and high-fat diets are to blame for America’s 
ever-growing waistline and incidence of chronic disease. The author, 
Dean Ornish, founder of the nonprofit Preventive Medicine Research 
Institute, is no newcomer to these nutrition debates. For 37 years
 he has been touting the benefits of very low-fat, high-carbohydrate, 
vegetarian diets for preventing and reversing heart disease. But the 
research he cites to back up his op–ed claims is tenuous at best. 
Nutrition is complex but there is little evidence our country’s 
worsening metabolic ills are the fault of protein or fat. If anything, 
our attempts to eat less fat in recent decades have made things worse.
Ornish begins his piece with a misleading statistic. Despite being told 
to eat less fat, he says, Americans have been doing the opposite: They 
have “actually consumed 67 percent more added fat, 39 percent more sugar
 and 41 percent more meat in 2000 than they had in 1950 and 24.5 percent
 more calories than they had in 1970.” Yes, Americans have been eating 
more fat, sugar and meat, but we have also been eating more vegetables 
and fruits (pdf)—because we have been eating more of everything. 
What’s more relevant to the discussion is this fact: During the time 
in which the prevalence of obesity in the U.S. nearly tripled, the 
percentage of calories Americans consumed from protein and fat actually dropped
 whereas the percentage of calories Americans ingested from 
carbohydrates—one of the nutrient groups Ornish says we should eat more 
of—increased.
 Could it be that our attempts to reduce fat have in fact been part of 
the problem? Some scientists think so. “I believe the low-fat message 
promoted the obesity epidemic,” says Lyn Steffen, a nutritional 
epidemiologist at the University of Minnesota School of Public Health. 
That’s in part because when we cut out fat, we began eating foods that 
were worse for us.[...]
The point here is not that Ornish’s diet—a low-fat, whole food, 
plant-based approach—is necessarily bad. It’s almost certainly healthier
 than the highly processed, refined-carbohydrate-rich diet most 
Americans consume today. But Ornish’s arguments against protein and fat 
are weak, simplistic and, in a way, irrelevant. A food or nutrient can 
be healthy without requiring that all other foods or nutrients be 
unhealthy. And categorizing entire nutrient groups as “good” or “bad” is
 facile. “It’s hard to move the science forward when there are so many 
stakeholders who say ‘this is the right diet and no other one could 
possibly be right,’” Bazzano says. Plus, discouraging the intake of 
entire macronutrient groups can backfire. When people dutifully cut down
 on fat in the 1980s and 1990s, they replaced much of it with high-sugar
 and high-calorie processed foods (think: Snackwell’s). If we start 
fearing protein, too, what will we fill our plates with instead? History
 tells us it’s not going to be spinach.

Required reading on this topic is Gary Taubes's "Good Calories, Bad Calories," an exhaustive study of the current science, and a debunking of the conventional low-fat, low-calorie idea of weight loss, for which there is zero scientific proof. He goes into the sad history of why this idea came to be accepted -- it is eye-opening to say the least.
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